Send us Fan MailJesse Mendelsohn and Michael Grosberg from Model N discuss why U.S. pricing complexity is spreading globally, the collapse of the PBM rebate model, what's really driving the pharmaceutical manufacturing boom, and why direct-to-consumer discount programs won't solve America's drug access problem.00:00 Introduction to Life Science Success Podcast00:34 Pressing Issues in Pharmaceutical Manufacturing00:51 Introducing the Experts from Model N03:08 Understanding International Reference Pricing04:14 Impact of US Pricing on Global Drug Launches09:26 Challenges with Pharmacy Benefit Managers16:29 Domestic Manufacturing Boom in Pharmaceuticals23:08 AI in Drug Discovery and Personalized Medicine29:03 Access and Policy Discussion30:01 Direct to Consumer Pricing31:32 TrumpRx Overview33:11 Compliance Challenges38:30 Pharmaceutical Revenue Management41:38 AI in Life Sciences48:35 Future of Life Sciences50:45 Concerns and Challenges53:52 Excitement in Current Work55:54 Conclusion and Final Thoughts