The Longevity & Lifestyle Podcast

What if sweetness itself isn’t the real problem?In this episode, Claudia welcomes back Sakiko Reuterskiöld, founder and CEO of NOMOSU, to explore the science of sugar, fructose, fiber, cravings, sweeteners, the microbiome, and metabolic health. Sakiko explains why many people may be blaming the wrong thing when it comes to blood sugar, weight gain, and long-term metabolic dysfunction and why the bigger issue may be excess sugar, especially liquid fructose, low fiber intake, and the structure of modern foods.They discuss the difference between sweet taste and metabolic harm, why liquid fructose may be especially damaging over time, how fiber supports satiety, insulin sensitivity, and gut health, and what the science really says about stevia, erythritol, cacao, and so-called “healthy” sugars. This episode is especially relevant for anyone who wants better energy, fewer cravings, improved blood sugar control, and a smarter, more science-backed relationship with sweetness.Ready to upgrade your health, energy, and longevity? Download my free 10 Life & Longevity Hacks Playbook and start living smarter, stronger, and longer → https://longevity-and-lifestyle.com/freebie Timestamps00:00 Intro and Sakiko’s mission to rethink sweetness through metabolic and gut health 02:08 Why sweetness itself may not be the real problem 03:57 Glucose vs fructose — and why fructose can be more harmful over time 05:32 Why liquid fructose is especially damaging for metabolic health 06:44 Sakiko’s personal story with sugar, cravings, and energy 08:39 Dates, honey, maple syrup, and agave — are they really healthier? 12:18 The biggest misinformation around sweeteners and health headlines 13:55 Stevia, monk fruit, erythritol, xylitol, allulose, and sweet proteins explained 16:19 Erythritol controversy — what people may be misunderstanding 19:38 Stevia deep dive — insulin sensitivity, cravings, and misconceptions 24:17 Have we lost the ability to taste real sweetness? 26:57 How to reset your palate and reduce sugar cravings 27:45 Why fiber is foundational for metabolic health and healthspan 29:49 Fiber, satiety hormones, GLP-1, and fullness signals 30:46 Easy fiber upgrades and practical daily strategies 31:12 Fiber, cravings, short-chain fatty acids, and the microbiome 32:28 Inulin, fructose handling, and the gut-liver connection 34:00 Fiber and cardiovascular health, LDL, ApoB, and inflammation 44:33 Where to find Sakiko and learn more about NOMOSULearn more about Peptides for High Performance; https://peptidefoundation.lumaralearn.com/ If you enjoy science-backed conversations on longevity, metabolic health, biohacking, brain health, women’s health, and performance optimization, subscribe and turn on notifications so you don’t miss upcoming episodes.#longevity #metabolichealth #bloodsugar #fiber #guthealth #biohacking #nutrition #healthoptimization #sugar

In this episode of the Longevity & Lifestyle Podcast, Claudia sits down with Jay Campbell to unpack the truth about peptides, GLP-1s, hormone optimization, metabolic health, and the future of longevity medicine.Jay explains why peptides are tools, not magic bullets, why hormone optimization should come before advanced peptide protocols, and how many people are misunderstanding GLP-1s entirely. They also explore microdosing, growth hormone peptides, mitochondrial support, NAD, nootropic peptides, metabolic dysfunction, and the serious risks of fake or contaminated peptide products.If you want to better understand what actually matters before using peptides or GLP-1s, and how to think about fat loss, performance, and long-term optimization more intelligently, this episode is packed with practical insight.Learn more about Peptides for High Performance; https://peptidefoundation.lumaralearn.com/Timestamps 00:00 Introduction to Jay Campbell 01:20 Why peptides and AI are tools, not magic bullets 23:11 Modern toxic load, obesity, and metabolic dysfunction 28:17 Why hormone optimization comes first 31:26 Why peptides could change the future of medicine 39:41 Peptide categories explained 40:54 GLP-1s, tirzepatide, retatrutide, and what most people get wrong 45:03 Growth hormone peptides and the “holy trinity” stack 46:06 Hormones, GLP-1 microdosing, and fat loss synergy 46:46 Mitochondrial peptides and advanced performance protocols 52:36 NAD, mitochondrial support, and energy 56:19 Nootropic peptides and brain optimization 1:00:48 The peptide quality problem and how to avoid fake products 1:02:16 Final thoughts#Longevity #Peptides #GLP1 #HormoneOptimization #MetabolicHealth #Biohacking #JayCampbell

What if your microbiome is influencing far more than digestion - from your brain and immune system to aging, energy and chronic disease risk?In this fascinating episode, Dr. Momchil “Momo” Vuyisich joins Claudia to unpack the science of the microbiome, microbial function and personalized nutrition.We explore:• Why Your Gut Microbiome Shapes Human Health • The Difference Between Microbes and Microbial Function • How Gut Bacteria Influence Brain Health and Cognition • Why Antibiotic Overuse May Increase Chronic Disease Risk • The Role of Fermented Foods and Probiotics • Why Personalized Nutrition Is the Future of Healthcare • The Importance of Keystone Species Like Akkermansia • How Food Preservatives and Modern Diets Affect the Gut • Why Testing and Data Create Actionable Health Insights • The Future of Microbiome Science and Precision HealthThis conversation is a powerful reminder that longevity starts with understanding the invisible ecosystem living inside us.Timestamps 00:00 - Why chronic stress may be destroying your body 00:38 - Dr. Momchilo Vuyisich’s background and work at Viome 01:33 - Why humans are an ecosystem, not just an individual 03:58 - Why fiber is essential for feeding the microbiome 04:52 - How the microbiome is shaped at birth 06:31 - Why asthma, food allergies, and IBD may be rising 08:13 - How mothers can support a healthier microbiome before pregnancy 09:40 - The hidden long-term cost of antibiotics 11:06 - How preservatives and non-organic meat may harm the microbiome 12:22 - How to rewild your microbiome after disruption 16:46 - Why some keystone strains are so hard to restore 18:19 - Microbial function vs. microbial strains 20:49 - How microbial metabolites affect the brain and body 24:25 - Why personalized nutrition may matter more than generic healthy eating 27:20 - The four pillars of health: food, exercise, Zen, and sleep 29:58 - Why there is no single optimal diet for everyone 32:34 - Minimum effective exercise for longevity 34:21 - Why stress management is non-negotiable 37:48 - Why sleep sets up your entire next day 39:33 - Are naps helpful or harmful? 40:22 - The microbiome and neurodivergence 43:07 - Can chronic disease become preventable? 44:31 - Preventive maintenance for the human body 46:34 - How the microbiome may influence immune memory 48:13 - What Dr. Vuyisich is building at Viome now 51:15 - Where to follow Dr. Vuyisich and learn moreSubscribe to Longevity & Lifestyle for science-backed insights on longevity, health optimization, brain health, metabolic health, women’s health, and performance.#microbiome #guthealth #longevity #healthoptimization #immunity #brainhealth #metabolichealth #personalizednutrition #biohacking #healthyaging

What if your body starts warning you long before real symptoms appear? In this episode, Claudia sits down with Mila Reeves to unpack what real health ownership looks like - from reading your body’s early signals to understanding NAD+, peptides, supplement quality, diagnostics, hormones, energy, and the dangerous gap between good science and good marketing.Maila shares her personal path into longevity, why she believes prevention is no longer optional, how NAD+ moved from addiction clinics into the mainstream longevity world, what most people misunderstand about delivery methods, why quality control in supplements matters far more than most consumers realize, and how to think more clearly about peptides, personalization, and aging well.This is a practical conversation on how to stay sharp, energized, and resilient for longer - without falling for hype.Timestamps00:00 - Your body gives signals before breakdown01:33 - Intro to Maila Reeves03:07 - Maila’s origin story: fashion, law, strategy, and longevity06:35 - The problem with snake oil in longevity08:36 - What to check before buying supplements09:13 - When longevity became personal12:59 - Visualizing the future: how do you want to age?13:59 - Why people still outsource their health16:42 - The knowledge gap in medicine and women’s health19:01 - Why your doctor is not always right for your body21:27 - Mila’s non-negotiables: positivity, gratitude, NAD, NAC, vitamin D22:51 - What NAD+ actually is24:27 - Why NAD+ was first used in addiction recovery26:20 - IV vs subcutaneous vs capsules28:05 - Why delivery method matters for NAD+30:02 - What’s the most effective way to take NAD+?31:55 - Claudia’s experience using NAD+ for travel and energy33:29 - Hair, libido, brain clarity, skin, sleep, and hormones35:12 - Who should not take NAD+36:12 - Why quality and certification matter38:06 - Peptides explained simply40:49 - Why peptides are becoming so popular41:25 - The fundamentals still matter most42:40 - Final message: prevention is not optionalReady to upgrade your health, energy, and longevity? Download my free 10 Life & Longevity Hacks Playbook and start living smarter, stronger, and longer → https://longevity-and-lifestyle.com/freebie#longevity #NAD #peptides #biohacking #healthoptimization #womenshealth #supplements #antiaging #podcast #ClaudiaVonBoeselager

What if your home is quietly accelerating your aging… or actively supporting your longevity?In this solo episode, Claudia explores one of the most overlooked pillars of health: your environment.We spend over 90% of our lives indoors - yet most people focus only on nutrition, exercise, and supplements while ignoring the space their body lives in.Claudia breaks down:The five key environmental factors shaping your biologyWhy air, water, light, materials and nervous system load matterHow your environment impacts energy, sleep, inflammation and performanceThe role of mitochondria and energy allocation in healthWhy you can’t optimize your biology in a survival stateThe truth about “healthy” swaps like saltwater poolsWhy wellness real estate is becoming the future of luxury and investmentThis episode is an invitation to shift from optimizing your body… to optimizing the environment that supports it.Watch the full episode here