A deep dive into agentic AI for bioinformatics: what agents are, how they work, the state of the art in 2026, and why ClawBio's specification layer — SKILL.md — changes how we package and share computational biology methods. Covers the OpenClaw architecture, MCP protocol, Galaxy integration, 7 hard challenges, 6 opportunities, and ClawBio's roadmap from 25 skills to a full platform. Includes a call to action for the ClawBio Hackathon: Agentic Genomics at Imperial College on 19 March 2026.