The Open Loop with Chay Carter

In this episode of The Open Loop, Chay Carter is joined by Sudhin Shah and Jeremy Hill, Co-Founders of Cognitive Signals. Sudhin is an Associate Professor of Neuroscience in Radiology at Weill Cornell Medicine, where her research focuses on cognitive recovery following brain injury. Jeremy is CTO of Cognitive Signals, bringing expertise in neuroscience, brain-computer interfaces, machine learning and software development. Together, they share how their research into disorders of consciousness led to the creation of Cognitive Signals: a company developing EEG-based technology to help assess cognitive function in patients who cannot communicate through speech or movement. We explore how the technology uses audiobooks and brain responses to spoken language to investigate comprehension, and why bringing these tools out of research laboratories and into clinical settings could change how patients are assessed after severe brain injury. Key takeaways: 🔹 Why patients who appear unresponsive may still retain awareness and cognitive function 🔹 How Cognitive Signals uses EEG and spoken language to investigate comprehension 🔹 Why traditional bedside assessments can miss signs of cognitive activity 🔹 How the company is working towards more accessible assessment in ICUs and clinical settings 🔹 Where the technology could expand, from recovery after anaesthesia to longer-term cognitive monitoring Host: Chay Carter Founder, Carter Sciences | Co-Founder, Reccy Neuro LinkedIn: https://www.linkedin.com/in/chay-carter/ Guests: Sudhin Shah, PhD Co-Founder, Cognitive Signals | Associate Professor of Neuroscience in Radiology, Weill Cornell Medicine LinkedIn: https://www.linkedin.com/in/sudhin-shah-b85841b Jeremy Hill, DPhil Co-Founder and CTO, Cognitive Signals LinkedIn: https://www.linkedin.com/in/njhill Company: Cognitive Signals Website: https://cognitivesignals.com/ The Open Loop is a podcast exploring the people, companies, and ideas shaping the future of neurotechnology. 🔔 Subscribe for weekly conversations with the founders, researchers, operators, and industry leaders building what comes next in brain health, medicine, and technology. If you enjoyed this episode, please subscribe, leave a review, and share it with someone interested in neurotechnology. New episodes of The Open Loop drop weekly. Sponsor: This episode is sponsored by Reccy Neuro — the home of neurotech. Jobs, companies, investors, events, Cortex industry intelligence, and specialist resources for the neurotech market. Learn more about Reccy Neuro here: https://neuro.reccy.dev/

In this episode of The Open Loop, Chay Carter is joined by Mikko Karvinen, CEO of Nexstim, a Finnish neurotechnology company developing navigated transcranial magnetic stimulation (nTMS). Mikko shares his journey from CFO to CEO during a challenging period for Nexstim, and how the company refocused its strategy around precision brain mapping, neuromodulation and commercial growth. We explore how Nexstim uses patient-specific MRI data to guide TMS stimulation, its applications in neurosurgical planning and depression treatment, and why accurate targeting is becoming increasingly important in neurotechnology. Mikko also discusses Nexstim's partnerships with Brainlab and Sinaptica Therapeutics, the potential of TMS-EEG in Alzheimer's research, and the opportunities ahead for precision neuromodulation. Key takeaways: 🔹 How navigated TMS uses brain imaging to deliver more precise and repeatable stimulation 🔹 How Nexstim navigated financial challenges and evolved its commercial strategy 🔹 Why brain mapping is becoming increasingly important in neurosurgical planning 🔹 How the Brainlab partnership is supporting Nexstim's global expansion 🔹 Why TMS-EEG, personalised targeting and Alzheimer's research could open new opportunities for neuromodulation Host: Chay Carter Founder, Carter Sciences | Co-Founder, Reccy Neuro LinkedIn: https://www.linkedin.com/in/chay-carter/ Guest: Mikko Karvinen CEO, Nexstim Plc LinkedIn: https://www.linkedin.com/in/mikko-karvinen-4909a/ Company: Nexstim Website: https://www.nexstim.com/ The Open Loop is a podcast exploring the people, companies, and ideas shaping the future of neurotechnology. 🔔 Subscribe for weekly conversations with the founders, researchers, operators, and industry leaders building what comes next in brain health, medicine, and technology. If you enjoyed this episode, please subscribe, leave a review, and share it with someone interested in neurotechnology. New episodes of The Open Loop drop weekly. Sponsor: This episode is sponsored by Reccy Neuro — the home of neurotech. Jobs, companies, investors, events, Cortex industry intelligence, and specialist resources for the neurotech market. Learn more about Reccy Neuro here: https://neuro.reccy.dev/

In this episode of The Open Loop, Chay Carter is joined by Mark Slater, Co-Founder of Otherside. Mark shares how his personal experience living with epilepsy, combined with a career in healthcare advertising and brand strategy, led him to build Otherside alongside Jon Nelson, a neuroscience agency bringing lived experience into the heart of healthcare communications. We explore why groundbreaking neurotechnology often struggles to connect with the people who need it, and how more human communication can help bridge the gap between scientific innovation and real-world impact. Mark also shares the story behind the Otherside Lounge, a community initiative creating spaces for people living with epilepsy to connect, share experiences, and help shape the future of brain health. Key takeaways: 🔹 Why lived experience is essential to effective neurotechnology communication 🔹 How Mark's experience with epilepsy shaped the creation of Otherside 🔹 Why healthcare language often fails to reflect patients' everyday experiences 🔹 How the Otherside Lounge is creating meaningful connections within the epilepsy community 🔹 Why trust, accessibility and patient understanding matter as consumer neurotechnology continues to grow Host: Chay Carter Founder, Carter Sciences | Co-Founder, Reccy Neuro LinkedIn: https://www.linkedin.com/in/chay-carter/ Guest: Mark Slater Co-Founder, Otherside | Board Member, Pediatric Epilepsy Research Consortium (PERC) LinkedIn: https://www.linkedin.com/in/mark-slater-other-side/ Otherside: https://otherside.health/ The Open Loop is a podcast exploring the people, companies, and ideas shaping the future of neurotechnology. 🔔 Subscribe for weekly conversations with the founders, researchers, operators, and industry leaders building what comes next in brain health, medicine, and technology. If you enjoyed this episode, please subscribe, leave a review, and share it with someone interested in neurotechnology. New episodes of The Open Loop drop weekly. Sponsor: This episode is sponsored by Reccy Neuro — the home of neurotech. Jobs, companies, investors, events, Cortex industry intelligence, and specialist resources for the neurotech market. Learn more about Reccy Neuro here: https://neuro.reccy.dev/

In this episode of The Open Loop, Chay Carter is joined by Ryan Glatt and Lauren Sergio of NERON. Ryan is a Brain Health Coach and Director of the FitBrain℠ Program at Pacific Neuroscience Institute, where his work focuses on brain health, exercise science, clinical exergaming, dual-task training, and cognitive wellness. Lauren is a Professor and neuroscientist at York University whose work focuses on movement control, cognitive-motor integration, and how the brain coordinates thinking and movement. We explore how NERON is using simple movement-based tasks to assess more complex brain communication, and why thinking while moving could become a valuable part of brain health measurement. Ryan and Lauren also discuss ageing, concussion, fall risk, sport, military applications, and the challenge of making brain health assessment more accessible outside traditional clinical settings. Key takeaways: 🔹 Why thinking and moving together can reveal more than cognition or movement alone 🔹 How neuromotor and visuomotor control relate to everyday brain health 🔹 Why dual-task assessment may help identify risk earlier than traditional screening tools 🔹 How NERON uses simple movement tasks to assess complex brain communication 🔹 Where this technology could be used across ageing, concussion, sport, military and community health settings Host: Chay Carter Founder, Carter Sciences | Co-Founder, Reccy Neuro LinkedIn: https://www.linkedin.com/in/chay-carter/ Guests: Ryan Glatt Brain Health Coach | Director, FitBrain℠ Program at Pacific Neuroscience Institute LinkedIn: https://www.linkedin.com/in/ryan-glatt-ms-cpt-nbc-hwc-50ba3664/ Lauren Sergio Professor and Neuroscientist, York University LinkedIn: https://ca.linkedin.com/in/lauren-sergio-2793351a The Open Loop is a podcast exploring the people, companies, and ideas shaping the future of neurotechnology. 🔔 Subscribe for weekly conversations with the founders, researchers, operators, and industry leaders building what comes next in brain health, medicine, and technology. If you enjoyed this episode, please subscribe, leave a review, and share it with someone interested in neurotechnology. New episodes of The Open Loop drop weekly. Sponsor: This episode is sponsored by Reccy Neuro — the home of neurotech. Jobs, companies, investors, events, Cortex industry intelligence, and specialist resources for the neurotech market. Learn more about Reccy Neuro here: https://neuro.reccy.dev/

In this episode of The Open Loop, Chay Carter is joined by Adam Fraser, Chief Operating Officer at Omniscient Neurotechnology. Adam shares how Omniscient is taking connectomics out of the lab and into clinical practice, using AI and MRI data to help decode the brain’s structural and functional networks. We explore how connectomics can support neurosurgical planning today, why brain network mapping could become important across DBS, stroke, coma, epilepsy and psychiatry, and what it takes to build a scalable neurotechnology platform inside the US healthcare system. Adam also discusses Omniscient’s go-to-market journey, reimbursement, medical education, the company’s US focus, the role of AI in brain mapping, and why mental health remains a long-term North Star for the business. Key takeaways: 🔹 What connectomics means and why it matters for brain health 🔹 How structural and functional connectomes act like “roads and traffic” for the brain 🔹 Why neurosurgical planning was Omniscient’s first major clinical focus 🔹 How connectomics could support future work in DBS, stroke, coma, epilepsy and psychiatry 🔹 Why bringing new neurotechnology into the US healthcare system requires evidence, reimbursement and medical education Host: Chay Carter Founder, Carter Sciences | Co-Founder, Reccy Neuro LinkedIn: https://www.linkedin.com/in/chay-carter/ Guest: Adam Fraser Chief Operating Officer, Omniscient Neurotechnology LinkedIn: https://www.linkedin.com/in/adam-fraser-23202133/ The Open Loop is a podcast exploring the people, companies, and ideas shaping the future of neurotechnology. 🔔 Subscribe for weekly conversations with the founders, researchers, operators, and industry leaders building what comes next in brain health, medicine, and technology. If you enjoyed this episode, please subscribe, leave a review, and share it with someone interested in neurotechnology. New episodes of The Open Loop drop weekly. Sponsor: This episode is sponsored by Reccy Neuro — the home of neurotech. Jobs, companies, investors, events, Cortex industry intelligence, and specialist resources for the neurotech market. Learn more about Reccy Neuro here: https://neuro.reccy.dev/