Navigated TMS and Precision Brain Stimulation with Mikko Karvinen

In this episode of The Open Loop, Chay Carter is joined by Mikko Karvinen, CEO of Nexstim, a Finnish neurotechnology company developing navigated transcranial magnetic stimulation (nTMS). Mikko shares his journey from CFO to CEO during a challenging period for Nexstim, and how the company refocused its strategy around precision brain mapping, neuromodulation and commercial growth. We explore how Nexstim uses patient-specific MRI data to guide TMS stimulation, its applications in neurosurgical planning and depression treatment, and why accurate targeting is becoming increasingly important in neurotechnology. Mikko also discusses Nexstim's partnerships with Brainlab and Sinaptica Therapeutics, the potential of TMS-EEG in Alzheimer's research, and the opportunities ahead for precision neuromodulation. Key takeaways: 🔹 How navigated TMS uses brain imaging to deliver more precise and repeatable stimulation 🔹 How Nexstim navigated financial challenges and evolved its commercial strategy 🔹 Why brain mapping is becoming increasingly important in neurosurgical planning 🔹 How the Brainlab partnership is supporting Nexstim's global expansion 🔹 Why TMS-EEG, personalised targeting and Alzheimer's research could open new opportunities for neuromodulation Host: Chay Carter Founder, Carter Sciences | Co-Founder, Reccy Neuro LinkedIn: https://www.linkedin.com/in/chay-carter/ Guest: Mikko Karvinen CEO, Nexstim Plc LinkedIn: https://www.linkedin.com/in/mikko-karvinen-4909a/ Company: Nexstim Website: https://www.nexstim.com/ The Open Loop is a podcast exploring the people, companies, and ideas shaping the future of neurotechnology. 🔔 Subscribe for weekly conversations with the founders, researchers, operators, and industry leaders building what comes next in brain health, medicine, and technology. If you enjoyed this episode, please subscribe, leave a review, and share it with someone interested in neurotechnology. New episodes of The Open Loop drop weekly. Sponsor: This episode is sponsored by Reccy Neuro — the home of neurotech. Jobs, companies, investors, events, Cortex industry intelligence, and specialist resources for the neurotech market. Learn more about Reccy Neuro here: https://neuro.reccy.dev/