Weight Loss Decoded - GLP Edition

Sharon Polsky

Details

Welcome to the Weight Loss Decoded Podcast, where science meets practical strategies for sustainable weight management, metabolic health, and longevity. I'm Sharon Polsky—author of Weight Loss Decoded: Unlocking the Truth About GLP Weight Loss Medications, health coach, and host. Each episode features leading physicians, researchers, fitness professionals, and industry experts who help separate evidence from hype surrounding GLP-1 medications, obesity, nutrition, exercise, body composition, hormones, and long-term weight management. Season 2 expands beyond the basics of GLP-1 medications to explore the bigger picture of lasting health. Together, we tackle topics including microdosing GLP-1s, menopause and weight gain, strength training, body composition, compounding pharmacies, peptides, hormone optimization, coaching, lifestyle medicine, metabolic health, and the future of obesity treatment. You'll also hear inspiring conversations with individuals sharing their real-world experiences—their successes, setbacks, and lessons learned—so you can better navigate your own health journey with confidence. Whether you're considering GLP-1 medications, currently taking them, supporting patients as a healthcare professional, or simply looking for evidence-based guidance on living healthier, the Weight Loss Decoded Podcast delivers trusted expert insights, practical takeaways, and actionable strategies you can apply immediately. Evidence over hype. Real conversations. Practical strategies. Join us as we decode the science of weight loss and empower you to make informed decisions for lifelong health.

Recent Episodes

OCT 1, 2026
Behavioral Coaching for Lasting Weight Loss with Ben Wilson
Struggling with weight loss after 50? Discover sustainable, real-world strategies for lasting results from fitness coach Ben Wilson. He's a personal trainer and behavioral coaching expert with over two decades of experience helping people achieve their health goals. Ben and I get into the strategies and building blocks that make healthy habits stick. Things like sleep, stress management, relationships, exercise, and nutrition. Ben Wilson shares why meeting people where they’re at is key, why it’s never too late to start making changes (even at 90 years old!), and how motivation, adaptable routines, and supportive social circles can transform your approach to lifelong health. Plus, we tackle topics especially relevant to adults over 50: sustainable results, overcoming setbacks, building confidence after years of yo-yo dieting, and the role of GLP-1 medications in making changes that last. By the end, you’ll have practical, realistic advice to set manageable goals, develop healthy habits, and grow old gracefully—no matter your starting point. What You’ll Learn: Why meeting yourself where you are is crucial (and what that looks like in practice) The power of small, adaptable routines instead of rigid plans How social support and community transform your weight loss journey Ways to break mental blocks, stay motivated, and rethink “non-responder” myths with GLP-1 Simple, effective tweaks to exercise, sleep, and nutrition habits that work at any age 5 Frequently Asked Questions about Losing Weight After 50 Can you really start getting healthier after age 50? Absolutely. Ben Wilson shares that improvements in strength and mobility are possible even in your 70s, 80s, and beyond. What role does GLP-1 medication play in weight loss? GLP-1s are a useful tool, but long-term success relies on changing habits and behaviors alongside medication use. How important is community or social support in weight management? Very. Building social connections and joining supportive groups greatly enhances motivation and success. What’s the best way to overcome mental blocks and lack of motivation? Meet yourself where you are, set realistic goals, seek social support, and practice tools like journaling or stress reduction. Is rapid weight loss on GLP-1 or any program recommended? No. Both speakers stress that slower, steadier weight loss (about 2–3 pounds per month) is more sustainable and helps prevent regaining weight. If you’re ready to cut through the noise and get a clearer, more honest understanding of GLP weight loss medications, pick up Sharon Polsky’s book, Weight Loss Decoded: Unlocking The Truth about GLP Weight Loss Medications. It’s a practical next step for anyone who wants trusted guidance and more confidence in making informed decisions about their weight-loss journey. Get your copy here. In hardback, paperback, and as an audiobook. Think of our podcast as your personal weight loss toolbox, filled with the tools you need to build and maintain your health. Whether you're considering GLP-1 medications or looking for holistic weight management strategies, this podcast is designed to empower you with knowledge and support. Visit my website! Find me on YouTube Find me on Instagram @SharonPolsky https://uppbeat.io/t/matrika/when-we-were-young License code: 3VR556DKJQFEFZSU The Weight Loss Decoded - GLP Edition Podcast is for informational and educational purposes only. The content shared here represents the views and opinions of the host and guests and should not be considered medical, health, or professional advice. This podcast is not a substitute for individualized care from qualified medical providers. Please consult with your healthcare provider before making decisions that may affect your health and wellness. Any statements about treatments, health protocols, or medications discussed are based on personal experience or professional expertise and may not be suitable for everyone. Always seek personalized advice from a licensed healthcare professional who understands your specific health needs.
48 MIN
SEP 15, 2026
The Future of Peptides And GLP-1s With Dr. Jim LaValle
Are peptides and GLP-1s safe for weight loss? Sharon Polsky and Jim LaValle break down what adults over 50 need to know. Ready to cut through the noise around peptides and GLP-1s for weight loss and healthy aging? Sharon Polsky sits down with Jim LaValle, RPh, CCN, DHM, DHPh—renowned educator, clinical pharmacist, and metabolic health advocate—to separate the facts from fiction on the future of peptide therapies, with essential takeaways for adults 50 and over. In this episode, you’ll get an insider perspective on: What happened at the FDA regarding peptide approvals and why it matters The critical difference between safe, legitimate peptides and risky gray market options Real-world data on peptide safety, effectiveness, and what “compounding” really means How peptides (including, but not limited to, GLP-1s) can support weight loss, menopause, joint health, and longevity Why lifestyle foundations, like sleep, stress management, nutrition, and exercise, cannot be ignored, and how to make peptides work better for you If you’re ready to cut through the noise and get a clearer, more honest understanding of GLP weight loss medications, pick up Sharon Polsky’s book, Weight Loss Decoded: Unlocking The Truth about GLP Weight Loss Medications. It’s a practical next step for anyone who wants trusted guidance and more confidence in making informed decisions about their weight-loss journey. Get your copy here. In hardback, paperback, and as an audiobook. Key Takeaways Safe peptide therapy depends on clinical oversight and quality compounding, not gray or black market sources Compounded GLP-1s and other peptides can be powerful tools for weight loss, but should always accompany healthy lifestyle changes Peptides are not miracle cures, but can help when individualized to your needs and taken under medical supervision Non-GLP-1 peptides like MOTS-c, Epitalon, and tesafensine offer options for those where GLP-1s don’t work—or alongside them for better results Adults over 50 can benefit from peptide therapies, but must be cautious, seek out experienced and certified providers, and avoid shortcuts Unlock a smarter, safer approach to weight loss and healthy aging! Moments 06:13 FDA info and safety presentation 09:56 Understanding medication titration 12:39 Defending the role of compounding 16:51 Ensuring Safe Pharmaceutical Compounding 19:46 Reconstituting gray market peptides 21:39 MOTS-c for menopause relief 24:37 Discussing weight loss compounds 28:12 Switching patients back to tirzepatide 31:28 Peptide therapy experiences 36:24 Importance of Sleep for Muscle Growth 38:14 Using growth hormone for recovery 41:18 Helping Dad with Weight Loss 45:39 Dealing with an autoimmune condition Think of our podcast as your personal weight loss toolbox, filled with the tools you need to build and maintain your health. Whether you're considering GLP-1 medications or looking for holistic weight management strategies, this podcast is designed to empower you with knowledge and support. Visit my website! Find me on YouTube Find me on Instagram @SharonPolsky https://uppbeat.io/t/matrika/when-we-were-young License code: 3VR556DKJQFEFZSU The Weight Loss Decoded - GLP Edition Podcast is for informational and educational purposes only. The content shared here represents the views and opinions of the host and guests and should not be considered medical, health, or professional advice. This podcast is not a substitute for individualized care from qualified medical providers. Please consult with your healthcare provider before making decisions that may affect your health and wellness. Any statements about treatments, health protocols, or medications discussed are based on personal experience or professional expertise and may not be suitable for everyone. Always seek personalized advice from a licensed healthcare professional who understands your specific health needs.
48 MIN
SEP 1, 2026
Sleep Strategies For Weight Loss and Better Health with Andrew Colski
Discover how optimizing your sleep routines can accelerate weight loss, boost mental health, and transform your family’s well-being. Are you stuck in a weight loss plateau, struggling with restless nights, or exhausted from trying all the quick fixes? I welcome behavioral sleep medicine expert Andrew Colski to provide the missing links between sleep, weight loss, and true well-being. You’ll learn practical sleep strategies for both adults and kids, why nutrition and habits are more important than any supplement, and get actionable advice to start sleeping, and living, better tonight. In this episode, you’ll learn: Why sleep is foundational for muscle growth, weight loss, and mental health (00:16) The difference between behavioral sleep science and prescription-focused sleep approaches (01:05) How nutrition, caffeine, sugar, and screen time sabotage sleep for both kids and adults (10:02, 13:28) Evidence-based routines: how to set—and stick to—a healthy sleep schedule for the whole family (21:38) How wearable sleep devices can cause more anxiety than results—and where to focus instead (28:53) Top five must-have steps to improve your sleep, starting tonight (32:56) The often-missed link: why fixing diet is the first step to fixing your sleep (38:06) Transform how you (and your kids) sleep for lasting energy, clarity, and results on your weight loss journey! 5 Frequently Asked Questions Why Sleep is Crucial for Weight Loss 1. Why is sleep crucial for weight loss and overall health? Without sufficient sleep, your body can’t build muscle, recover, or regulate appetite and mood. Chronic sleep deprivation undermines weight loss and mental health (00:26). 2. What’s the difference between behavioral sleep medicine and traditional sleep medicine? Behavioral sleep medicine addresses the habits, environments, and routines affecting sleep (like insomnia and device use), while MDs focus more on diagnosing conditions and prescribing medication (01:05). 3. How does diet impact sleep? High sugar, processed foods, and caffeine can disrupt both child and adult sleep, making it harder to fall and stay asleep. A nourishing diet with real foods supports quality rest (10:02; 38:06). 4. What are the top tips for improving sleep routines for families? Prioritize quality diet, regular exercise, a device-free and dark bedroom, a consistent sleep schedule, and treating the bed as a sleep-only space (33:02). 5. Are wearable sleep trackers reliable? Most wearables aren’t as accurate as sleep labs and can increase anxiety about sleep. The focus should be on real-life results and behavioral consistency, not device data (29:28). If you’re ready to cut through the noise and get a clearer, more honest understanding of GLP weight loss medications, pick up Sharon Polsky’s book, Weight Loss Decoded: Unlocking The Truth about GLP Weight Loss Medications. It’s a practical next step for anyone who wants trusted guidance and more confidence in making informed decisions about their weight-loss journey. Get your copy here. In hardback, paperback, and as an audiobook. Think of our podcast as your personal weight loss toolbox, filled with the tools you need to build and maintain your health. Whether you're considering GLP-1 medications or looking for holistic weight management strategies, this podcast is designed to empower you with knowledge and support. Visit my website! Find me on YouTube Find me on Instagram @SharonPolsky https://uppbeat.io/t/matrika/when-we-were-young License code: 3VR556DKJQFEFZSU Copyright 2026 Sharon Polsky The Weight Loss Decoded - GLP Edition Podcast is for informational and educational purposes only. The content shared here represents the views and opinions of the host and guests and should not be considered medical, health, or professional advice. This podcast is not a substitute for individualized care from qualified medical providers. Please consult with your healthcare provider before making decisions that may affect your health and wellness. Any statements about treatments, health protocols, or medications discussed are based on personal experience or professional expertise and may not be suitable for everyone. Always seek personalized advice from a licensed healthcare professional who understands your specific health needs.
36 MIN
AUG 15, 2026
"Why Gary is a Dick" with Kim Constable, The Sculpted Vegan
Are fitness programs failing to address what women really need? Join Sharon Polsky and Kim Constable as they tackle GLP-1 weight loss medications, the booming peptide industry, and the myths that hold people back from real progress. Joining me is Kim Constable, powerhouse entrepreneur, professional bodybuilder, and creator of the world’s largest online vegan bodybuilding platform, Sculpted Vegan. If you know Kim from Instagram or TikTok, you’ve probably seen her hilarious “Gary the Personal Trainer” series, where she takes aim at those in the fitness industry who oversimplify lifelong struggles with obesity. Kim Constable shares how a chance conversation led her to realize just how much GLP-1 medications like Ozempic and Mounjaro were reshaping the weight loss landscape. She opens up about the challenges and backlash she encountered for supporting GLP-1 use, including guilt and judgment from both the fitness industry and social media, and why she chose to fully embrace and advocate for these tools as part of her clients’ journeys. You’ll hear Kim Constable and I discuss not only the profound impact GLP-1s have had on weight loss, but also their broader health benefits. From reducing inflammation and pain, to improving metabolic health, brain clarity, and even healing menopausal symptoms. The episode also delves into the synergy of peptides, with both sharing personal stories of transformation and their favorite compounds for everything from increased focus to skin and joint repair. If you’re fed up with old-school “calories in, calories out” advice, confused by all the conflicting information on GLP-1s, or seeking inspiration to reclaim your health without shame or guilt, this episode brings clarity, empathy, and practical insights for anyone ready for change. Key Takeaways: Why GLP-1 medications like semaglutide and tirzepatide have changed the weight loss industry and helped thousands “just exhale” and see results for the first time The hidden benefits of peptides (beyond weight loss), including decreased inflammation, improved sleep and cognitive clarity, and dramatic pain relief Why guilt and shame don’t work, and how a supportive approach is driving real transformation for women at every stage How to identify which peptide or GLP-1 to try based on your top health concern, plus practical tips for dosing and working with medical providers Kim’s firsthand experience launching a peptide company, her top picks for hair, skin, and energy, and why the fitness industry needs to adapt Think of our podcast as your personal weight loss toolbox, filled with the tools you need to build and maintain your health. Whether you're considering GLP-1 medications or looking for holistic weight management strategies, this podcast is designed to empower you with knowledge and support. If you’re ready to cut through the noise and get a clearer, more honest understanding of GLP weight loss medications, pick up Sharon Polsky’s book, Weight Loss Decoded: Unlocking The Truth about GLP Weight Loss Medications. It’s a practical next step for anyone who wants trusted guidance and more confidence in making informed decisions about their weight-loss journey. Get your copy here. In hardback, paperback, and as an audiobook. Visit my website! Find me on YouTube Find me on Instagram @SharonPolsky The Weight Loss Decoded - GLP Edition Podcast is for informational and educational purposes only. The content shared here represents the views and opinions of the host and guests and should not be considered medical, health, or professional advice. This podcast is not a substitute for individualized care from qualified medical providers. Please consult with your healthcare provider before making decisions that may affect your health and wellness. Any statements about treatments, health protocols, or medications discussed are based on personal experience or professional expertise and may not be suitable for everyone. Always seek personalized advice from a licensed healthcare professional who understands your specific health needs. https://uppbeat.io/t/matrika/when-we-were-young License code: 3VR556DKJQFEFZSU Copyright 2026 Sharon Polsky
31 MIN
AUG 1, 2026
Separating Fact from Hype in the New Era of GLP-1s
Are you overwhelmed by conflicting information on GLP-1 weight loss medications? This episode with Dr. Bowen clears the confusion and brings you actionable, up-to-date answers. I talk with Dr. Bowen to discuss the key issues facing anyone interested in GLP-1s: from navigating TikTok myths to practical nutrition advice, cost planning, and the future of these powerful medications. Drawing from patient experiences and real-world coaching, we break down how to protect lean mass, manage set point, and adopt lifestyle changes for lasting results. What’s Covered: The difference between short-form myths and long-form facts about GLP-1s How to approach food, protein, fiber, and healthy fats for sustainable weight loss Strategies for ramping on and off GLP-1 medications to avoid rebound weight gain The future of GLP-1s: new generations, accessibility, and alternative uses (like sleep apnea and neuroprotection) Why personalized nutrition, muscle maintenance, and a gradual approach are crucial to success Key Takeaways: Short-form videos oversimplify GLP-1s; informed decisions require deeper content Nutrition needs balance,. Protein, fiber, and healthy fats matter, not just calories Plan your budget and medication timeline (expect at least 10 months on GLP-1s) Off-ramping is essential: abrupt stops can cause major setbacks GLP-1s are a tool, not a standalone solution. Pair them with lasting lifestyle changes If you’re ready to cut through the noise and get a clearer, more honest understanding of GLP weight loss medications, pick up Sharon Polsky’s book, Weight Loss Decoded: Unlocking The Truth about GLP Weight Loss Medications. It’s a practical next step for anyone who wants trusted guidance and more confidence in making informed decisions about their weight-loss journey. Get your copy here. In hardback, paperback, and as an audiobook. 5 Frequently Asked Questions about GLP-1's What are GLP-1 weight loss medications, and are they all the same? No. GLP-1s like Ozempic, Wegovy, and tirzepatide (Mounjaro, Zepbound) have different FDA approvals and effects—many people confuse them or use the wrong terminology. Can you lose lean muscle mass on GLP-1 medications? Not necessarily. Sharon Polsky and Dr. Bowen explain that with adequate protein, fiber, and healthy fats, along with lifestyle changes, most patients can maintain or even gain lean muscle. How long do you need to stay on GLP-1 weight loss medications? Plan for a minimum of 10 months—5 months to lose weight and 5 months to properly off-ramp and stabilize. Going off abruptly can lead to rapid weight regain. Are GLP-1s only for weight loss? No. They're used for diabetes, but evolving evidence shows benefits for metabolic health, sleep apnea, brain protection, and even helping with smoking or gambling cessation in some individuals. What should you do before starting GLP-1 weight loss medications? Educate yourself with reliable, long-form resources, plan your budget, find the right medical support, and be ready to make lasting nutrition and lifestyle changes for real success. Think of our podcast as your personal weight loss toolbox, filled with the tools you need to build and maintain your health. Whether you're considering GLP-1 medications or looking for holistic weight management strategies, this podcast is designed to empower you with knowledge and support. Visit my website! Find me on YouTube Find me on Instagram @SharonPolsky https://uppbeat.io/t/matrika/when-we-were-young License code: 3VR556DKJQFEFZSU The Weight Loss Decoded - GLP Edition Podcast is for informational and educational purposes only. The content shared here represents the views and opinions of the host and guests and should not be considered medical, health, or professional advice. This podcast is not a substitute for individualized care from qualified medical providers. Please consult with your healthcare provider before making decisions that may affect your health and wellness. Any statements about treatments, health protocols, or medications discussed are based on personal experience or professional expertise and may not be suitable for everyone. Always seek personalized advice from a licensed healthcare professional who understands your specific health needs. Copyright 2026 Sharon Polsky
40 MIN