Beyond Longevity
Beyond Longevity

Beyond Longevity

Daphna Stern

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Episodes

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Beyond Longevity is a deep-dive podcast exploring the cutting edge of longevity science. Through conversations with leading researchers, clinicians, and innovators who are redefining health and longevity, the show unpacks the evidence behind living longer and healthier. Each episode translates complex research into clear, thoughtful discussions, decoding the future of ageing one conversation at a time.

Recent Episodes

Why Longer lives Are Changing Work, Business and Society, with Avivah Wittenberg-Cox
APR 6, 2026
Why Longer lives Are Changing Work, Business and Society, with Avivah Wittenberg-Cox
This week’s guest is Avivah Wittenberg-Cox. Avivah advises leaders on gender and generational balance, the future of work, and the longevity economy. She hosts the podcast 4-Quarter Lives, publishes the Substack Elderberries, and writes regularly for Forbes and Harvard Business Review. She is Visiting Faculty at Oxford’s Saïd Business School, co-directs the Longevity Leadership Programme at Católica Lisbon, and has given three TED Talks.In this episode, Avivah and Daphna explore how longer lives are reshaping work, business, and society. Avivah argues that longevity is not just a health story but a structural shift that is forcing organisations to rethink how they are built, how careers unfold, and how different generations work together.She explains why the old pyramid model of the workforce is giving way to a more square demographic reality, with far more balance between younger and older generations than most institutions were designed for. That shift brings real pressure, from pensions to healthcare, but also major opportunities for businesses willing to adapt.The conversation looks at why older workers are still too often overlooked, what businesses lose when they fail to value experience, and why age-inclusive thinking is becoming a strategic advantage rather than a social add-on. More broadly, the episode challenges outdated assumptions about ageing and asks what it would mean to build a society that treats longer lives as a source of possibility, not decline.This episode is a reminder that longevity is not only changing how long we live, but how we work, lead, learn, and contribute across the course of our lives.https://www.avivahwittenbergcox.com/https://elderberries.substack.comhttps://elderberries.substack.com/podcasthttps://www.ted.com/search?q=Avivah+Wittenberg+Coxhttps://20-first.com/https://www.forbes.com/sites/avivahwittenbergcox/#61c5a38ebf1900:00 Longevity Meets Work02:06 Longevity Mega Trend03:09 Institutions Lag Behind05:37 From Gender To Age07:39 Women And Longer Lives10:08 Multi Stage Careers11:26 Rethinking Education Midlife15:29 Rebranding Old Age17:54 Opportunity And Ageism21:24 Fear Of Ageing And Happiness25:37 Goldman Sachs And AI27:17 Company First Mover Advantage28:43 Who Is Leading The Way29:52 Brands Embrace Pro Ageing30:21 Longevity In Hospitality31:12 Retirees As Consultants31:56 Why Leaders Miss Demographics35:29 Government Levers And Limits38:34 The Square Society Shift40:43 Measuring Longevity Readiness43:25 Advice Four Quarter Lives47:54 Designing A Four Quarter Life53:22 Ageing Better Than Expected54:46 Rapid Fire And Wrap Up
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58 MIN
Why Governments Still Ignore Ageing, and What Must Change with Dr Ilia Stambler
MAR 23, 2026
Why Governments Still Ignore Ageing, and What Must Change with Dr Ilia Stambler
What does it take to turn longevity science into real-world policy? In this episode, Daphna speaks with Dr Ilia Stambler, historian of longevity, published author, Chair of the International Longevity Alliance (ILA), and Chief Science Officer and Chairman of Vetek (Seniority) Association, about why advocacy and ecosystem-building may be just as important as the science itself.Dr Stambler shares how the ILA has grown into a global network connecting 76 nonprofits across 66 countries, organising international conferences, and running the annual Longevity Day (1st October) and Longevity Month (October) campaigns. He points to concrete wins, including efforts to support the inclusion of ageing-related conditions in the ICD and the WHO's work programme.The conversation gets honest about the real barriers to progress. Dr Stambler argues the problem isn't convincing governments that ageing matters, it's getting them to treat it with urgency. Despite ageing representing one of the largest disease burdens globally, it remains chronically underfunded and deprioritised, in part because the research timelines required don't fit neatly into political cycles.He also reflects on the deeper intellectual questions underpinning the field: how to balance holism and reductionism, why historical perspective is essential for longevity researchers, and how the same patterns of enthusiasm, scepticism, and neglect have repeated across centuries of rejuvenation science.Looking ahead to 2030, Dr Stambler highlights the need for better public education, evidence-based criteria for evaluating interventions, and growing grassroots motivation, because ultimately, he believes, a longer and healthier life begins with wanting one.In This Episode:How the ILA operates across 66 countries and what it's achievedWhy governments acknowledge ageing but still fail to act on itThe long funding timelines longevity research demands — and why that's a political problemWhich countries are currently leading on longevity policyWhy solo science isn't enough and advocacy changes outcomesThe "Death Valley of ideas" and how to get research across itBalancing holism and reductionism in longevity scienceWhy the history of rejuvenation science keeps repeating itselfWhat meaningful success in this field actually looks like.Ilia Stambler, PhDChairman and CSO. Vetek (Seniority) Association – The Movement for Longevity and Quality of Life, Israel http://www.longevityisrael.org/Chairman. International Longevity Alliance (ILA) http://www.longevityalliance.org/Fellow. Department of Science, Technology and Society, Bar-Ilan University, Israel https://sts.biu.ac.il/Author. A History of Life-Extensionism in the Twentieth Century; Longevity Promotion: Multidisciplinary Perspectives; Healthy Longevity: Policies and Practices http://longevityhistory.comhttps://www.longevityhistory.com/about-the-author/00:00 Welcome and Guest Intro01:28 Staler Background and Mission03:18 What the ILA Does04:04 Key Wins and Campaigns05:25 Public Misconceptions07:27 Getting Governments to Act09:14 Funding Research Long Term10:49 Education and Conferences12:05 Which Countries Lead15:22 Why Advocacy Beats Solo Science17:38 Advocacy Success Stories20:48 Breaking Longevity Silos21:23 Holism vs Reductionism22:28 Why History Matters24:17 Death Valley of Ideas25:49 Rejuvenation Patterns Repeat27:42 Misunderstood Longevity History29:22 Balance and Modesty31:23 Measuring Real Success34:59 Making Longevity Policy36:09 Rapid Fire Takeaways38:58 Final Wrap Up
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40 MIN
AI, Biomarkers and the Future of Longevity Medicine, with Elio Verhoef, Co-Founder of LongevAI
MAR 16, 2026
AI, Biomarkers and the Future of Longevity Medicine, with Elio Verhoef, Co-Founder of LongevAI
In this episode, Daphna sits down with Elio, co-founder of LongevAI, a platform using artificial intelligence to help longevity clinics analyse biomarker data, streamline documentation, and build personalised client plans.With a background in computer science and a lifelong passion for health optimisation, Elio offers a grounded, honest perspective on what AI in longevity medicine can do today, and where the limits still lie.______________What We Cover• How LongevAI was founded and what problem it solves for longevity clinics• What it means to automate clinical documentation without removing the clinician from the process• How AI interprets biomarker data, and why speed and accuracy both play a role• The hallucination problem: what it is, why it happens, and how it is being managed• Data privacy, GDPR compliance, and anonymisation in clinical AI tools• The importance of human oversight, why the clinician must always approve before anything reaches the client• How AI and clinicians can learn from each other in a feedback loop• Wearable integration and the role of continuous vs snapshot data• Where AI in longevity is heading in two to five years, including gene therapy modelling and whole-cell simulation• Why younger people are beginning to engage with longevity, and what still holds them backAbout the GuestElio is the co-founder of LongevAI, a software platform built for longevity clinics. He holds a double bachelor's degree in Computer Science and Information Science, and has been focused on health optimisation and AI since his teens. He co-founded LongevAI in December 2024 alongside Cosmina Druica, whom he met through a longevity meetup community in the Netherlands.🔗 longevai.comEnjoyed this episode? Please subscribe, leave a review on Apple Podcasts or Spotify, and share with anyone curious about the future of longevity medicine.Beyond Longevity is hosted by Daphna Stern · beyond-longevity.co.ukIn this episode:00:00 Welcome and Guest Intro01:52 Elio Background and Origins04:01 What Lev AI Does05:06 Automating Clinic Workflows07:52 Speed vs Accuracy11:45 Oversight and Patient Trust12:57 Privacy and GDPR Security13:56 How the Model Improves15:06 Limits Data and Hallucinations21:37 Training and Integrations23:45 Personal Biomarker Walkthrough28:34 Explaining LLMs to non-tech people33:38 Future of AI and Longevity35:32 Young People and Longevity39:56 Rapid Fire Questions43:45 Wrap Up and Key Takeaways
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45 MIN
Why Do We Age? Dr Bradley Elliott on Biomarkers, Muscle, and What Longevity Science Still Doesn’t Know
MAR 9, 2026
Why Do We Age? Dr Bradley Elliott on Biomarkers, Muscle, and What Longevity Science Still Doesn’t Know
Dr Bradley Elliott — physiologist, university lecturer, and a trustee and Communications Lead at the British Society for Research on Ageing — joins host Daphna for a refreshingly honest conversation about what longevity science actually knows and what we still cannot explain.This episode cuts through the certainty. We talk about biomarkers and biological age, why many measurements may be tracking effects rather than causes, we discuss extracellular vesicles and the surprising limit of science. Dr Bradley discusses some of his papers and related research, and our conversation challenges much of the conventional wisdom in the longevity space.What we cover:-Why we still do not know what fundamentally causes ageing — and why every “root cause” often leads to something deeper-What biomarkers really measure, what they can and cannot tell you, and which markers are most worth tracking right now-Biological age vs chronological age: where the concept is useful, and where it gets overclaimed-Why muscle is one of the most underrated “health organs” in ageing — and what it supports beyond strength-Exercise for longevity: the evidence-based basics, plus what matters most for consistency and adherence-“It is not too late”: what studies in very old adults suggest about strength gains later in life-Extracellular vesicles: the hidden communication system between cells, and why it is getting so much attention-Wearables: why they can still be useful even when the numbers are not perfectly accurateThis is a fascinating episode with someone who knows how to communicate science and make it relatableLinks to Dr Bradley Elliot:- https://www.westminster.ac.uk/about-us/our-people/directory/elliott-bradley- https://bsra.org.uk/bradley-elliott-2/- https://www.bradelliott.online/Papers & Research Referenced• Perri et al. (2025) — Delphi review identifying 14 biomarkers of ageing for use in human research (co-authored by Dr Elliott)' https://pubmed.ncbi.nlm.nih.gov/39708300/• Lady V Barrios-Silva et al. — Activin subfamily peptides and prediction of age and physical function (undergraduate-led research, University of Westminster)https://pubmed.ncbi.nlm.nih.gov/30178598/• Dr Yvoni Kyriakidou (PhD) — Exercise-induced muscle damage in young and old men; extracellular vesicle characterisation post-exercisehttps://pubmed.ncbi.nlm.nih.gov/34650440/• Dr Niharika Duggal (University of Birmingham) — Masters athletes and immune function; older athletes vs. age-matched non-athleteshttps://pubmed.ncbi.nlm.nih.gov/29517845/• Stephen Harridge (King's College London) — Resistance training in 90+ year olds; gains in muscle strength and mass in the oldest oldhttps://pubmed.ncbi.nlm.nih.gov/10398199/• Science paper on genetic contribution to longevity — updated estimate shifting genetic contribution to ~50% (noted with editorial by Dr Elliott)https://www.science.org/doi/10.1126/science.adz1187https://theconversation.com/what-new-twins-study-reveals-about-genes-environment-and-longevity-274763https://www.ukbiobank.ac.uk/If you enjoyed this episode, we'd love it if you took 60 seconds to leave us a review on Apple Podcasts or Spotify. It genuinely helps more people find the show and means we can keep bringing you honest, science-backed conversations like this one. Thank youhttps://beyond-longevity.co.uk/Chapters:00:00 Why We Age01:52 Meet Bradley Elliot03:07 From Sports Science05:32 Defining Ageing07:03 Mechanisms And Theories09:29 Biomarkers Explained13:02 Delphi Biomarker List16:59 Myostatin Study Story21:25 Actionable Biomarkers26:07 Wearables And Accuracy27:38 Endocrine Fingerprints30:11 Muscle And Healthy Ageing33:21 Athletes And Immunity34:26 Muscle Mass And Healthspan36:36 Exercise Dose Guidelines39:42 Resistance Training Plateau40:42 Lifestyle Versus Genetics42:42 Muscle Damage Study44:44 Extracellular Vesicles Explained46:49 Young Blood Controversy50:08 Dream Research With Omics56:55 What People Misjudge58:43 It’s Never Too Late01:02:41 Rapid Fire And Wrap01:04:31 Final Takeaways
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65 MIN